Hi Eric,
The final result is mildly cleaned up, and have removed a lot of the high frequency noise of the resulting output from Photoscan, but was literally a few second job using sculpt tools to smooth it down without loosing its accuracy.
I pretty much use the default settings that Photoscan has when you first start it up after install. The real trick is getting the sharpest image possible with a good amount of depth of field within the frame. With the right amount of light and perfect image quality, the results get smoother and smother within the package. Also the use of masks can really improve alignment. I only use exact/high for reconstruction. Also, I'm not using a single camera to capture with and have created my own multi camera rig so I'm able to capture facial expressions in an instant. This example was done using three cameras that create two stereo pairs.
I've been using Di3D systems for the last 7 years, now using alternate tech, have treated Photoscan in a similar manner. Knowing Di extremely well, I know what those guys do to make their scan data look good, and smoothing the resulting mesh (noise reduction) is part of their pipeline. Hope it becomes part of PhotoScan at some point.
Currently waiting for the next Photoscan update, as Dmitry mentioned that there should be a fix to the exact reconstruction method so the split that occurs is no more. This gives issue when it comes to clean up.
Attached an image of the result within Photoscan, which is highly comparable with results from Di. Only if the software had the ability to do noise reduction to the final result. No masking used for this, and no holes filled.