Hello David,
For low resolution imagery I can recommend the following alignment parameters:
- Highest accuracy,
- Reference preselection enabled (providing that the coordinate information is available), Generic option - disabled,
- 40 000 key points,
- 8 000 tie points,
- adaptive camera model fitting - disabled.
Additionally you can fix the calibration parameters prior to the camera alignment operation via the Camera Calibration dialog. To do that you need to input the focal length and sensor pixel size in mm (unless loaded automatically from EXIF) to the corresponding fields of the dialog.