Hello hanscastrop1,
during alignment/optimization Metashape calculates/adjusts interior orientation parameters. Set of parameters is stored per group in Tools Menu -> Camera Calibration dialog. So if you have sets of images taken by different cameras or in different conditions, it is strongly recommended to split the calibration groups for such subsets.
So you can have images captured by different cameras in the same chunk and be processed together, but the calibration groups should be split accordingly prior to the alignment step.