Hello Frank,
Bounding Box can be resized and repositioned using Python script, but to do that some criterion should be suggest. For example, center of the bounding box can be estimated based on camera positions (the simplest way is to average their locations) and the size could be selected as a distance from the center to any camera.
It's just an example of what can be done.
Also you can place static markers in scene. It will allow to set up the coordinate system and scale of the model, thus the bounding box size and center can be defined in absolute units.
If you have already any idea of the BB definition, but need any assistance in scripting, let me know.