Basic back-of-the-napkin estimations seem to indicate that choosing a graphics card based on LuxMark tests for OpenCL isn't a bad idea. Of course, the guy running 8 Titans is on top of the rankings. If you want the best and don't mind paying for it, wait for the GM200 Maxwell Titan or the R9 390X which should be out later this spring, the R9 390X looks like it might have the edge, but hey, I'm an nvidia guy. Used, I came down on the side of the 780ti for price/performance, but if you want more bang something in the titan range isn't a bad idea. If you have great cooling (especially if you want to run more than 1 gpu) AMD offers some good alternatives. Realistically, at the top end of the gaming level you're probably not going to choose a bad card.