Hi Tom !
It's normal that it takes so long time if you've disabled the preselection. The soft try to find matches between each pictures and the 1799 others...
If your pictures are good quality ones and give enough overlapping, you firstly should use the generic preselection, which create a first rough alignment in low resolution in order to know which pictures have been taken closely. It will reduce the calculation time a lot, even more if it's 1800 nadiral pictures above a huge area.
Then, it's you have quite accurate position (guess 5m is the best you can expect without expensive geodetic material), you can also use the reference preselection, which choose pictures according to their 3D coordinates. Don't forget to be carfeul about the accuracy you give to your pictures positions !
About another point, even I'm not a specialist, I'm quite sure you cannot make the most of your two quaddro GPU is you only have a I5 CPU. But I deeply hope you didn't forget to enabled OpenCL process with your two GPUs.
Regards